Across TCGA patient cohorts, ZNF431 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,922 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ZNF431-associated proteins across cancer lineages are LMNB2, MRM3, and PRDX3. Each is linked with ZNF431 in more than 4 cancer types. Because this analysis shows association rather than direction, both ZNF431-to-partner and partner-to-ZNF431 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF431→partner) and Y-score (partner→ZNF431) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	LMNB2 →	+0.310	+0.602	<.001	<.001	3	5
PDAC	MRM3 →	-0.354	-0.299	<.001	.002	3	4
OV	PRDX3 →	-0.332	-0.390	.003	.004	3	4
GBM	RANBP3 →	+0.205	+0.446	<.001	<.001	3	4
GBM	MBD3 →	+0.578	+0.573	<.001	<.001	3	4
LSCC	ARMC6 →	+0.349	+0.888	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,922 associations by consensus.

Exploration

ZNF431 survival (RNA) · tumor vs normal (RNA) · all ZNF431 data types