ZNF430

Across TCGA patient cohorts, ZNF430 mutation is significantly associated with the RNA expression of many other genes, with 3,492 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF430-associated genes across cancer lineages are FKBP1AP2, PIGW, and OR7G3. Each is linked with ZNF430 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF430-to-partner and partner-to-ZNF430 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FKBP1AP2 grouped by ZNF430-low versus ZNF430-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF430→partner) and Y-score (partner→ZNF430) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	FKBP1AP2 →	+0.166	+6.149	<.001	.002	3	3
UCEC	PIGW →	+0.604	+3.010	.002	<.001	3	3
HNSC	OR7G3 →	+0.070	+4.600	<.001	.001	3	3
HNSC	RNU6-238P →	+0.663	+4.084	<.001	.005	3	3
LIHC	MEMO1P3 →	+0.160	+5.355	<.001	.005	3	3
UCEC	MCM8 →	+0.597	+2.343	.003	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,492 associations by consensus.

FKBP1AP2 by ZNF430 expression — LIHC

Explore this box plot interactively →