ZNF430

Across TCGA cell cohorts, ZNF430 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,714 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZNF430-associated GO terms across cancer lineages are Regulation of mitotic metaphase/anaphase transition, Negative regulation of cell cycle process, and Regulation of double-strand break repair. Each is linked with ZNF430 in more than 11 cancer types. Because this analysis shows association rather than direction, both ZNF430-to-partner and partner-to-ZNF430 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of mitotic metaphase/anaphase transition grouped by ZNF430-low versus ZNF430-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF430→partner) and Y-score (partner→ZNF430) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Regulation of mitotic metaphase/anaphase transition →	+0.118	+1.058	<.001	<.001	3	12
SOFT_TISSUE	Negative regulation of cell cycle process →	+0.068	+0.777	<.001	<.001	3	12
SOFT_TISSUE	Regulation of double-strand break repair →	+0.081	+0.651	<.001	<.001	3	12
OVARY	Regulation of chromosome segregation →	+0.118	+0.979	<.001	<.001	3	12
SOFT_TISSUE	Positive regulation of chromosome segregation →	+0.108	+0.615	<.001	<.001	3	12
SOFT_TISSUE	Negative regulation of mitotic cell cycle →	+0.053	+0.895	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,714 associations by consensus.

Regulation of mitotic metaphase/anaphase transition by ZNF430 expression — OVARY

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