ZNF426

Across TCGA cell cohorts, ZNF426 mutation is significantly associated with the RNA expression of many other genes, with 13 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ZNF426-associated genes across cancer lineages are MSGN1, TAFA1, and MYL7. Each is linked with ZNF426 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF426-to-partner and partner-to-ZNF426 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MSGN1 grouped by ZNF426-low versus ZNF426-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF426→partner) and Y-score (partner→ZNF426) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	MSGN1 →	+0.082	+3.345	<.001	.007	3	1
LARGE_INTESTINE	TAFA1 →	+0.274	+3.688	<.001	.002	3	1
SKIN	MYL7 →	+0.465	+4.930	<.001	.001	3	1
SKIN	OR1L3 →	+0.022	+4.415	<.001	.007	3	1
LUNG_NSCLC_LUAD	POTED →	+0.156	+5.189	<.001	<.001	3	1
BLOOD_Lymphoma	CPN1 →	+0.141	+3.736	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

MSGN1 by ZNF426 expression — LARGE_INTESTINE

Explore this box plot interactively →