ZNF423

Across TCGA patient cohorts, ZNF423 protein abundance is significantly associated with the RNA expression of many other genes, with 5,936 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible ZNF423-associated genes across cancer lineages are HNRNPCP6, FGF9, and SPARCL1. Each is linked with ZNF423 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF423-to-partner and partner-to-ZNF423 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF423 versus HNRNPCP6 in OV, with a Pearson correlation of 0.94.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF423→partner) and Y-score (partner→ZNF423) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	HNRNPCP6 →	+4.320	+1.168	.003	.005	3	3
OV	FGF9 →	+2.253	+0.987	.009	.002	3	2
OV	SPARCL1 →	+1.450	+0.987	.003	.002	3	2
OV	MAGED4 →	+1.205	+0.987	<.001	.002	3	2
OV	CADM3 →	+1.219	+0.987	.008	.002	3	2
LUAD	H2BC13 →	-1.101	-0.429	.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,936 associations by consensus.

ZNF423 vs HNRNPCP6 — OV

Explore this scatter interactively →