Across TCGA patient cohorts, ZNF420 protein abundance is significantly associated with the RNA expression of many other genes, with 583 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ZNF420-associated genes across cancer lineages are CYTH4, MFNG, and NELFCD. Each is linked with ZNF420 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF420-to-partner and partner-to-ZNF420 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF420→partner) and Y-score (partner→ZNF420) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	CYTH4 →	-1.153	-0.462	.005	.009	3	1
LSCC	MFNG →	-0.931	-0.448	.001	.002	3	1
LSCC	NELFCD →	+1.007	+0.425	.001	.002	3	1
LSCC	CSNK2A1 →	+0.971	+0.473	.003	.001	3	1
LSCC	SEC23B →	+0.776	+0.686	.002	<.001	3	1
LSCC	NOP56 →	+0.991	+0.379	.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 583 associations by consensus.

Exploration

ZNF420 survival (RNA) · tumor vs normal (RNA) · all ZNF420 data types