Across TCGA patient cohorts, ZNF420 mutation is significantly associated with the RNA expression of many other genes, with 4,159 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF420-associated genes across cancer lineages are NCAPH2, HAUS5, and FANCE. Each is linked with ZNF420 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF420-to-partner and partner-to-ZNF420 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF420→partner) and Y-score (partner→ZNF420) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	NCAPH2 →	+0.663	+3.129	<.001	<.001	3	3
UCEC	HAUS5 →	+0.322	+1.568	.004	.001	3	3
UCEC	FANCE →	+0.429	+2.928	.002	<.001	3	3
UCEC	ITGB1BP1 →	+0.273	+2.408	.003	<.001	3	3
UCEC	GIN1 →	+0.244	+1.839	.002	.002	3	3
UCEC	PGAP2 →	+0.365	+2.203	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,159 associations by consensus.

Exploration

ZNF420 survival (RNA) · tumor vs normal (RNA) · all ZNF420 data types