Across TCGA cell cohorts, ZNF420 mutation is significantly associated with the RNA expression of many other genes, with 27 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF420-associated genes across cancer lineages are C5orf67, DEFB125, and PF4V1. Each is linked with ZNF420 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF420-to-partner and partner-to-ZNF420 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF420→partner) and Y-score (partner→ZNF420) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	C5orf67 →	+0.367	+4.017	.001	.007	3	1
LUNG_NSCLC_LUAD	DEFB125 →	+0.029	+5.662	<.001	.002	3	1
LARGE_INTESTINE	PF4V1 →	+0.214	+3.115	.001	.004	3	1
LARGE_INTESTINE	LHCGR →	+0.029	+3.297	.002	.002	3	1
LARGE_INTESTINE	TTLL8 →	+0.002	+3.700	<.001	.009	3	1
LARGE_INTESTINE	NAT8 →	+0.657	+3.443	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 27 associations by consensus.

Exploration

ZNF420 survival (RNA) · tumor vs normal (RNA) · all ZNF420 data types