ZNF419

Across TCGA patient cohorts, ZNF419 mutation is significantly associated with the RNA expression of many other genes, with 1,590 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF419-associated genes across cancer lineages are IFNWP9, LRR1, and H4C7. Each is linked with ZNF419 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF419-to-partner and partner-to-ZNF419 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IFNWP9 grouped by ZNF419-low versus ZNF419-high in ACC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF419→partner) and Y-score (partner→ZNF419) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ACC	IFNWP9 →	+0.061	+5.228	.004	.005	3	3
UCEC	LRR1 →	+0.523	+3.343	.006	.005	3	3
BRCA	H4C7 →	+0.239	+4.553	<.001	.005	3	2
ACC	OR11H6 →	+0.060	+5.228	<.001	.005	3	2
BLCA	LINC00391 →	+0.115	+4.605	.002	.004	3	2
ACC	SALL4P1 →	+0.035	+5.228	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,590 associations by consensus.

IFNWP9 by ZNF419 expression — ACC

Explore this box plot interactively →