long intergenic non-protein coding RNA 391Genealiases: []
Q-omics provides the consensus-scored LINC00391 profile across patient tissues and cancer cell-line models. LINC00391 expression is associated with patient survival in 16 of 34 cancer types, with the highest sampling consensus in KICH. Among the 18 cancer types available for tumor–normal comparison, LINC00391 is differentially expressed in 2, with the highest sampling consensus in LUSC. Additionally, LINC00391 RNA expression shows 8,213 significant protein co-abundance associations, with the highest sampling consensus in GBM. Together, these results highlight KICH, LUSC, and GBM as cancer lineages where LINC00391 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for LINC00391 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes LINC00391 survival associations across molecular data types. LINC00391 RNA expression shows survival associations in the most cancer types (16). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible LINC00391 RNA expression–survival associations across cancer types. High LINC00391 expression shows unfavorable associations in KICH, ACC, KIRC, BRCA and LUAD, but favorable associations in HNSC. The KICH Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify KICH as the clearest survival context for LINC00391 RNA expression.
This table summarizes LINC00391 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 2. The strongest signals are observed in LUSC for RNA.
This table ranks reproducible tumor–normal expression differences for LINC00391. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. LINC00391 shows higher tumor expression in LUSC and LUAD. The LUSC box plot shows higher LINC00391 RNA expression in tumor versus normal tissue (log2 FC = +0.057, t-test p < 0.001).
This table shows molecular features associated with LINC00391 in patient tissues and cancer cell lines. In patient samples, LINC00391 shows the broadest associations at the RNA and protein expression levels, with GBM recurring as the lineage with the largest associated feature set.
