ZNF417

Across TCGA cell cohorts, ZNF417 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,988 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZNF417-associated GO terms across cancer lineages are Negative regulation of myoblast fusion, Regulation of DNA-templated transcription initiation, and mRNA transport. Each is linked with ZNF417 in more than 17 cancer types. Because this analysis shows association rather than direction, both ZNF417-to-partner and partner-to-ZNF417 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of myoblast fusion grouped by ZNF417-low versus ZNF417-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF417→partner) and Y-score (partner→ZNF417) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Negative regulation of myoblast fusion →	+0.113	+1.145	<.001	<.001	3	18
SKIN	Regulation of DNA-templated transcription initiation →	+0.061	+0.694	<.001	.002	3	18
BONE	mRNA transport →	+0.108	+0.884	<.001	<.001	3	18
STOMACH	Nuclear export →	+0.087	+1.074	.008	.005	3	18
BONE	Regulatory ncRNA-mediated gene silencing →	+0.095	+1.452	<.001	<.001	3	18
BONE	Epigenetic regulation of gene expression →	+0.097	+1.302	<.001	<.001	3	18

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,988 associations by consensus.

Negative regulation of myoblast fusion by ZNF417 expression — UPPER_AERODIGESTIVE_TRACT

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