ZNF417

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, ZNF417 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. STOMACH shows the largest number of these associations.

The most reproducible ZNF417-associated genes across cancer lineages are TIMD4, KRTAP10-6, and KRTAP10-4. Each is linked with ZNF417 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF417-to-partner and partner-to-ZNF417 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TIMD4 grouped by ZNF417-low versus ZNF417-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF417→partner) and Y-score (partner→ZNF417) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SOFT_TISSUETIMD4 →+0.237+4.222<.001.00731
STOMACHKRTAP10-6 →+0.060+4.247<.001<.00131
STOMACHKRTAP10-4 →+0.108+3.632<.001.00931
SKINMINAR2 →+0.013+4.977<.001.00731
Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

TIMD4 by ZNF417 expression — SOFT_TISSUE

Box plot of TIMD4 in ZNF417-low vs ZNF417-high samples in SOFT_TISSUE.

Explore this box plot interactively →

Exploration