ZNF415

Across TCGA patient cohorts, ZNF415 mutation is significantly associated with the RNA expression of many other genes, with 3,308 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF415-associated genes across cancer lineages are SPANXC, SALL4P1, and RPL35AP3. Each is linked with ZNF415 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF415-to-partner and partner-to-ZNF415 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SPANXC grouped by ZNF415-low versus ZNF415-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF415→partner) and Y-score (partner→ZNF415) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	SPANXC →	+0.268	+3.283	<.001	.007	3	3
COAD	SALL4P1 →	+0.165	+3.145	<.001	.009	3	3
STAD	RPL35AP3 →	+0.293	+3.443	.001	.009	3	3
ESCA	TSPY15P →	+0.072	+5.954	<.001	.002	3	3
UCEC	LINC02079 →	+0.064	+2.471	<.001	.006	3	3
BLCA	MIR6790 →	+0.537	+6.307	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,308 associations by consensus.

SPANXC by ZNF415 expression — COAD

Explore this box plot interactively →