ZNF414

Across TCGA patient cohorts, ZNF414 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,342 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ZNF414-associated proteins across cancer lineages are FMNL1_S184, ILF3, and KHSRP. Each is linked with ZNF414 in more than 4 cancer types. Because this analysis shows association rather than direction, both ZNF414-to-partner and partner-to-ZNF414 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF414 versus FMNL1_S184 in LSCC, with a Pearson correlation of -0.36.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF414→partner) and Y-score (partner→ZNF414) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	FMNL1_S184 →	-0.632	-0.286	<.001	<.001	3	5
GBM	ILF3 →	+0.231	+0.361	<.001	<.001	3	5
GBM	KHSRP →	+0.294	+0.394	<.001	<.001	3	5
GBM	GBF1 →	-0.162	-0.425	<.001	<.001	3	4
GBM	VEZF1 →	+0.325	+0.353	<.001	<.001	3	4
GBM	RCOR3 →	+0.338	+0.396	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,342 associations by consensus.

ZNF414 vs FMNL1_S184 — LSCC

Explore this scatter interactively →