ZNF41

Across TCGA cell cohorts, ZNF41 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,723 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZNF41-associated GO terms across cancer lineages are Regulation of heterochromatin formation, Epigenetic regulation of gene expression, and Negative regulation of gene expression, epigenetic. Each is linked with ZNF41 in more than 15 cancer types. Because this analysis shows association rather than direction, both ZNF41-to-partner and partner-to-ZNF41 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of heterochromatin formation grouped by ZNF41-low versus ZNF41-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF41→partner) and Y-score (partner→ZNF41) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Regulation of heterochromatin formation →	+0.144	+0.787	.001	.002	3	16
OVARY	Epigenetic regulation of gene expression →	+0.072	+0.755	<.001	<.001	3	16
OVARY	Negative regulation of gene expression, epigenetic →	+0.080	+0.705	<.001	<.001	3	16
URINARY_TRACT	Regulation of heterochromatin organization →	+0.126	+0.658	.001	.007	2	16
OVARY	Heterochromatin formation →	+0.082	+0.686	<.001	<.001	3	15
OVARY	Heterochromatin organization →	+0.078	+0.838	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,723 associations by consensus.

Regulation of heterochromatin formation by ZNF41 expression — URINARY_TRACT

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