ZNF41

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, ZNF41 mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF41-associated genes across cancer lineages are OR10AG1, C1QTNF7, and ACER1. Each is linked with ZNF41 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF41-to-partner and partner-to-ZNF41 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR10AG1 grouped by ZNF41-low versus ZNF41-high in BLOOD_Myeloma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF41→partner) and Y-score (partner→ZNF41) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_MyelomaOR10AG1 →+0.023+4.807<.001.00631
LARGE_INTESTINEC1QTNF7 →+0.101+3.523<.001.00231
LARGE_INTESTINEACER1 →+0.108+3.408<.001<.00131
LARGE_INTESTINEH1-6 →+0.141+3.979<.001.00231
SKINPRAMEF33 →+0.017+4.415<.001.00731
LARGE_INTESTINECLEC18C →+0.136+3.555.003.00321
Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

OR10AG1 by ZNF41 expression — BLOOD_Myeloma

Box plot of OR10AG1 in ZNF41-low vs ZNF41-high samples in BLOOD_Myeloma.

Explore this box plot interactively →

Exploration