Across TCGA patient cohorts, ZNF398 RNA expression is significantly associated with the protein abundance of many other proteins, with 19,105 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ZNF398-associated proteins across cancer lineages are CDK5, TRIM24, and VSIR. Each is linked with ZNF398 in more than 5 cancer types. Because this analysis shows association rather than direction, both ZNF398-to-partner and partner-to-ZNF398 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF398→partner) and Y-score (partner→ZNF398) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	CDK5 →	+0.291	+0.600	<.001	<.001	3	6
GBM	TRIM24 →	+0.363	+0.310	<.001	<.001	3	6
GBM	VSIR →	-0.651	-0.463	<.001	<.001	3	6
LSCC	PUS7 →	+0.467	+0.579	<.001	<.001	3	5
HNSC	REPIN1 →	+0.436	+0.498	.002	<.001	3	5
GBM	RHEB →	+0.351	+0.398	.001	.005	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,105 associations by consensus.

Exploration

ZNF398 survival (RNA) · tumor vs normal (RNA) · all ZNF398 data types