Across TCGA cell cohorts, ZNF398 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,293 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZNF398-associated GO terms across cancer lineages are Negative regulation of chromatin organization, Positive regulation of isotype switching to IgG isotypes, and Nuclear export. Each is linked with ZNF398 in more than 12 cancer types. Because this analysis shows association rather than direction, both ZNF398-to-partner and partner-to-ZNF398 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF398→partner) and Y-score (partner→ZNF398) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Negative regulation of chromatin organization →	+0.158	+0.913	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Positive regulation of isotype switching to IgG isotypes →	+0.140	+0.770	<.001	<.001	3	13
BONE	Nuclear export →	+0.083	+0.833	.006	.003	3	13
BONE	RNA export from nucleus →	+0.113	+0.809	.005	.003	3	13
BONE	Regulation of chromatin organization →	+0.100	+0.874	<.001	<.001	3	12
BONE	Regulation of heterochromatin formation →	+0.109	+0.778	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,293 associations by consensus.

Exploration

ZNF398 survival (RNA) · tumor vs normal (RNA) · all ZNF398 data types