ZNF391

Across TCGA patient cohorts, ZNF391 protein abundance is significantly associated with the RNA expression of many other genes, with 4,165 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ZNF391-associated genes across cancer lineages are SCML2, PLEKHA1, and DRG2. Each is linked with ZNF391 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF391-to-partner and partner-to-ZNF391 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF391 versus SCML2 in LSCC, with a Pearson correlation of 0.53.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF391→partner) and Y-score (partner→ZNF391) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	SCML2 →	+1.425	+0.634	<.001	<.001	3	2
OV	PLEKHA1 →	+1.235	+1.230	.008	.004	3	2
OV	DRG2 →	+0.635	+0.779	.001	.007	3	2
OV	MDN1 →	+2.032	+0.779	<.001	.007	3	2
OV	MED23 →	+2.158	+1.296	<.001	.008	3	2
OV	TENT4A →	+1.254	+0.779	<.001	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,165 associations by consensus.

ZNF391 vs SCML2 — LSCC

Explore this scatter interactively →