ZNF391

Across TCGA cell cohorts, ZNF391 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,169 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZNF391-associated GO terms across cancer lineages are Protein localization to nucleus, Cytoplasmic translation, and Regulation of termination of RNA polymerase II transcription. Each is linked with ZNF391 in more than 11 cancer types. Because this analysis shows association rather than direction, both ZNF391-to-partner and partner-to-ZNF391 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein localization to nucleus grouped by ZNF391-low versus ZNF391-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF391→partner) and Y-score (partner→ZNF391) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Protein localization to nucleus →	+0.059	+0.946	<.001	.003	3	12
OVARY	Cytoplasmic translation →	+0.091	+1.016	<.001	<.001	3	11
OESOPHAGUS	Regulation of termination of RNA polymerase II transcription →	+0.165	+0.997	<.001	.005	3	11
PANCREAS	Regulation of termination of RNA polymerase II transcription, poly(A)-coupled →	+0.091	+0.794	<.001	.002	3	11
OESOPHAGUS	Regulation of termination of DNA-templated transcription →	+0.165	+0.997	<.001	.005	3	11
OVARY	Viral translation →	+0.071	+0.840	.001	.002	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,169 associations by consensus.

Protein localization to nucleus by ZNF391 expression — BREAST

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