ZNF384

Across TCGA patient cohorts, ZNF384 mutation is significantly associated with the RNA expression of many other genes, with 1,178 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF384-associated genes across cancer lineages are ATP1B2, IGHVIII-11-1, and TPPP3. Each is linked with ZNF384 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF384-to-partner and partner-to-ZNF384 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ATP1B2 grouped by ZNF384-low versus ZNF384-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF384→partner) and Y-score (partner→ZNF384) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ATP1B2 →	-0.710	-3.689	.004	.001	3	3
CESC	IGHVIII-11-1 →	+0.173	+5.891	.006	<.001	3	2
UCEC	TPPP3 →	-1.643	-3.584	.002	.002	3	2
UCEC	PKN3 →	+0.886	+3.732	<.001	<.001	3	2
UCEC	HSPA4L →	+0.782	+2.716	<.001	.003	3	2
UCEC	SFXN1 →	+0.554	+2.980	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,178 associations by consensus.

ATP1B2 by ZNF384 expression — UCEC

Explore this box plot interactively →