ZNF384

Across TCGA cell cohorts, ZNF384 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,194 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZNF384-associated GO terms across cancer lineages are Regulation of nucleotide-excision repair, Heterochromatin formation, and Negative regulation of gene expression, epigenetic. Each is linked with ZNF384 in more than 16 cancer types. Because this analysis shows association rather than direction, both ZNF384-to-partner and partner-to-ZNF384 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of nucleotide-excision repair grouped by ZNF384-low versus ZNF384-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF384→partner) and Y-score (partner→ZNF384) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Regulation of nucleotide-excision repair →	+0.124	+1.183	.002	<.001	3	17
BONE	Heterochromatin formation →	+0.070	+0.796	<.001	<.001	3	17
BONE	Negative regulation of gene expression, epigenetic →	+0.068	+0.796	<.001	<.001	3	17
BONE	Regulation of DNA repair →	+0.072	+0.876	<.001	<.001	3	17
BONE	Heterochromatin organization →	+0.067	+0.796	<.001	<.001	3	17
BONE	Epigenetic regulation of gene expression →	+0.063	+0.753	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,194 associations by consensus.

Regulation of nucleotide-excision repair by ZNF384 expression — BONE

Explore this box plot interactively →