Across TCGA patient cohorts, ZNF383 mutation is significantly associated with the total protein of many other genes, with 37 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF383-associated genes across cancer lineages are MSH2, mTOR_pS2448, and p70-S6K_pT389. Each is linked with ZNF383 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF383-to-partner and partner-to-ZNF383 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF383→partner) and Y-score (partner→ZNF383) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MSH2 →	-0.269	-1.848	<.001	.049	3	2
UCEC	mTOR_pS2448 →	-0.151	-1.571	.004	.032	3	2
UCEC	p70-S6K_pT389 →	-0.160	-2.000	.017	.029	3	2
UCEC	Bak →	+0.177	+1.584	.045	.034	3	2
UCEC	C-Raf →	+0.164	+2.000	.001	.009	3	2
UCEC	14-3-3_beta →	-0.102	-3.558	.004	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 37 associations by consensus.

Exploration

ZNF383 survival (RNA) · tumor vs normal (RNA) · all ZNF383 data types