Across TCGA cell cohorts, ZNF383 mutation is significantly associated with the RNA expression of many other genes, with 12 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible ZNF383-associated genes across cancer lineages are AVP, TSPAN16, and TRIM50. Each is linked with ZNF383 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF383-to-partner and partner-to-ZNF383 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF383→partner) and Y-score (partner→ZNF383) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	AVP →	+0.078	+4.392	<.001	.004	3	1
SOFT_TISSUE	TSPAN16 →	+0.084	+4.142	<.001	.003	3	1
SOFT_TISSUE	TRIM50 →	+0.074	+4.142	<.001	.003	3	1
SOFT_TISSUE	KCNA6 →	+0.012	+4.295	.001	.002	3	1
SOFT_TISSUE	FTMT →	+0.052	+4.392	<.001	.004	3	1
SOFT_TISSUE	IFNL1 →	+0.101	+3.865	.009	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

Exploration

ZNF383 survival (RNA) · tumor vs normal (RNA) · all ZNF383 data types