ZNF382

Across TCGA patient cohorts, ZNF382 mutation is significantly associated with the total protein of many other genes, with 24 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF382-associated genes across cancer lineages are ASNS, Notch1, and Caspase-7-cleavedD198. Each is linked with ZNF382 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF382-to-partner and partner-to-ZNF382 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ASNS grouped by ZNF382-low versus ZNF382-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF382→partner) and Y-score (partner→ZNF382) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ASNS →	+0.480	+2.807	<.001	.002	3	3
UCEC	Notch1 →	+0.143	+1.710	.004	.025	3	2
UCEC	Caspase-7-cleavedD198 →	+0.512	+1.827	.016	.015	3	2
UCEC	4E-BP1 →	+0.308	+3.351	.001	.005	3	2
UCEC	C-Raf →	+0.155	+1.700	.002	.042	3	2
SKCM	PKC-b-II_pS660 →	-0.345	-3.000	.040	.036	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 24 associations by consensus.

ASNS by ZNF382 expression — UCEC

Explore this box plot interactively →