ZNF382

Across TCGA cell cohorts, ZNF382 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,242 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZNF382-associated GO terms across cancer lineages are Epigenetic regulation of gene expression, Regulation of monoatomic ion transmembrane transport, and Regulation of monoatomic cation transmembrane transport. Each is linked with ZNF382 in more than 9 cancer types. Because this analysis shows association rather than direction, both ZNF382-to-partner and partner-to-ZNF382 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Epigenetic regulation of gene expression grouped by ZNF382-low versus ZNF382-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF382→partner) and Y-score (partner→ZNF382) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Epigenetic regulation of gene expression →	+0.054	+1.690	.002	<.001	3	10
LUNG_SCLC	Regulation of monoatomic ion transmembrane transport →	-0.077	-1.736	<.001	<.001	3	10
LUNG_SCLC	Regulation of monoatomic cation transmembrane transport →	-0.080	-1.886	<.001	<.001	3	9
SOFT_TISSUE	Termination of RNA polymerase II transcription →	+0.121	+0.928	<.001	<.001	3	9
BONE	Positive regulation of DNA repair →	+0.091	+1.262	<.001	<.001	3	9
LUNG_SCLC	Heterochromatin formation →	+0.072	+1.794	.001	.002	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,242 associations by consensus.

Epigenetic regulation of gene expression by ZNF382 expression — LUNG_SCLC

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