ZNF382

Across TCGA cell cohorts, ZNF382 mutation is significantly associated with the RNA expression of many other genes, with 29 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible ZNF382-associated genes across cancer lineages are USP17L15, CARTPT, and C16orf90. Each is linked with ZNF382 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF382-to-partner and partner-to-ZNF382 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, USP17L15 grouped by ZNF382-low versus ZNF382-high in OESOPHAGUS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF382→partner) and Y-score (partner→ZNF382) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	USP17L15 →	+0.136	+4.906	<.001	.006	3	1
SKIN	CARTPT →	+0.048	+4.273	<.001	.006	3	1
SKIN	C16orf90 →	+0.041	+4.467	<.001	.004	3	1
SKIN	UBTFL1 →	+0.024	+4.415	<.001	.007	3	1
LUNG_NSCLC_LUAD	USP29 →	+0.009	+4.078	<.001	.009	3	1
LUNG_NSCLC_LUAD	HMHB1 →	+0.051	+4.078	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 29 associations by consensus.

USP17L15 by ZNF382 expression — OESOPHAGUS

Explore this box plot interactively →