ZNF37BP

Across TCGA patient cohorts, ZNF37BP mutation is significantly associated with the RNA expression of many other genes, with 5,498 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF37BP-associated genes across cancer lineages are RNU6-226P, TCP11X3P, and RPL22P14. Each is linked with ZNF37BP in more than 3 cancer types. Because this analysis shows association rather than direction, both ZNF37BP-to-partner and partner-to-ZNF37BP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-226P grouped by ZNF37BP-low versus ZNF37BP-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF37BP→partner) and Y-score (partner→ZNF37BP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	RNU6-226P →	+0.713	+3.277	<.001	.004	3	4
UCEC	TCP11X3P →	+0.152	+1.454	.005	.003	3	4
BRCA	RPL22P14 →	+0.259	+5.311	<.001	.001	3	3
LUSC	DEFB121 →	+0.293	+4.780	<.001	.003	3	3
LUSC	MIR4654 →	+0.439	+4.257	<.001	.007	3	3
BLCA	LINC02451 →	+0.093	+5.038	<.001	.009	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,498 associations by consensus.

RNU6-226P by ZNF37BP expression — LUSC

Explore this box plot interactively →