ZNF37BP

Across TCGA patient cohorts, ZNF37BP mutation is significantly associated with the total protein of many other genes, with 55 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF37BP-associated genes across cancer lineages are JNK2, Mre11, and Notch1. Each is linked with ZNF37BP in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF37BP-to-partner and partner-to-ZNF37BP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, JNK2 grouped by ZNF37BP-low versus ZNF37BP-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF37BP→partner) and Y-score (partner→ZNF37BP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	JNK2 →	+0.148	+1.247	.029	.045	3	2
UCEC	Mre11 →	-0.066	-2.432	.024	.018	3	2
UCEC	Notch1 →	+0.134	+2.594	.005	.006	3	2
UCEC	p38-MAPK_pT180_Y182 →	-0.332	-1.234	.030	.045	3	2
UCEC	PCNA →	+0.275	+4.000	<.001	<.001	3	2
UCEC	PI3K-p85 →	-0.152	-1.874	.033	.049	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 55 associations by consensus.

JNK2 by ZNF37BP expression — UCEC

Explore this box plot interactively →