ZNF367

Across TCGA patient cohorts, ZNF367 mutation is significantly associated with the total protein of many other genes, with 6 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF367-associated genes across cancer lineages are eIF4E, Caspase-8, and JNK2. Each is linked with ZNF367 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF367-to-partner and partner-to-ZNF367 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, eIF4E grouped by ZNF367-low versus ZNF367-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF367→partner) and Y-score (partner→ZNF367) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	eIF4E →	+0.232	+2.459	.022	.020	3	1
UCEC	Caspase-8 →	-0.290	-2.973	.016	.035	3	1
UCEC	JNK2 →	+0.220	+3.584	.022	.002	2	1
UCEC	MEK1 →	+0.457	+3.169	.009	.019	2	1
UCEC	Tuberin →	+0.473	+2.459	<.001	.020	1	1
UCEC	C-Raf →	+0.158	+2.459	.022	.020	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

eIF4E by ZNF367 expression — UCEC

Explore this box plot interactively →