ZNF367

Across TCGA pan-cancer cohorts, ZNF367 RNA differs between tumor and matched normal tissue in 15 of 18 cancer types tested, making tumor–normal expression one of ZNF367’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where ZNF367 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types ZNF367 is over-expressed in tumor, although a few such as KICH show the opposite, repressed pattern.

HNSC, KICH, and COAD are the cancer types where ZNF367 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ZNF367 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	Male	III,IV	+1.311	<.001	11	view →
KICH	All	III,IV	−1.958	<.001	10	view →
COAD	Female	II,III,IV	+1.239	<.001	10	view →
LUSC	Female	All	+2.167	<.001	9	view →
STAD	Female	All	+1.748	<.001	9	view →
UCEC	All	III,IV	+1.965	<.001	8	view →
LUAD	Male	II,III,IV	+1.316	<.001	8	view →
BLCA	Female	III,IV	+1.248	.001	7	view →
BRCA	All	III,IV	+1.450	<.001	6	view →
THCA	All	All	+0.364	<.001	5	view →
KIRP	All	IV	+0.922	.038	4	view →
LIHC	All	III,IV	+0.836	.014	4	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 15 lineages.

ZNF367–HNSC

Open the HNSC breakdown →