ZNF367

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, ZNF367 mutation is significantly associated with the RNA expression of many other genes, with 10 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF367-associated genes across cancer lineages are ZNF804B, R3HDML, and BANF2. Each is linked with ZNF367 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF367-to-partner and partner-to-ZNF367 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ZNF804B grouped by ZNF367-low versus ZNF367-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF367→partner) and Y-score (partner→ZNF367) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINEZNF804B →+0.016+4.415<.001.00732
BLOOD_LymphomaR3HDML →+0.006+5.209<.001.00531
BLOOD_LymphomaBANF2 →+0.047+5.643<.001.00231
LUNG_NSCLC_LUADOR1D2 →+0.026+6.266<.001<.00131
BREASTDEFB108B →+0.176+5.781<.001.00131
LARGE_INTESTINEMAGEB4 →+0.022+4.415<.001.00731
Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

ZNF804B by ZNF367 expression — LARGE_INTESTINE

Box plot of ZNF804B in ZNF367-low vs ZNF367-high samples in LARGE_INTESTINE.

Explore this box plot interactively →

Exploration