ZNF367

Across TCGA cell cohorts, ZNF367 mutation is significantly associated with the mutation status of many other genes, with 1,849 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF367-associated genes across cancer lineages are KCNH4, BCOR, and ZBBX. Each is linked with ZNF367 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF367-to-partner and partner-to-ZNF367 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KCNH4 grouped by ZNF367-low versus ZNF367-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF367→partner) and Y-score (partner→ZNF367) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	KCNH4 →	+2.284	+3.925	.005	.005	1	3
BLOOD_Lymphoma	BCOR →	+2.710	+4.203	.008	.008	1	3
LARGE_INTESTINE	ZBBX →	+2.936	+4.471	.001	.001	1	3
LARGE_INTESTINE	LEMD3 →	+3.329	+3.799	.005	.005	1	3
LARGE_INTESTINE	DENND2C →	+3.744	+4.044	.003	.003	1	3
BREAST	CD22 →	+5.297	+5.297	.004	.004	1	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,849 associations by consensus.

KCNH4 by ZNF367 expression — LARGE_INTESTINE

Explore this box plot interactively →