ZNF362

Across TCGA patient cohorts, ZNF362 mutation is significantly associated with the RNA expression of many other genes, with 959 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF362-associated genes across cancer lineages are PPIAP81, PINCR, and MZT1P1. Each is linked with ZNF362 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF362-to-partner and partner-to-ZNF362 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PPIAP81 grouped by ZNF362-low versus ZNF362-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF362→partner) and Y-score (partner→ZNF362) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PPIAP81 →	+0.116	+1.377	<.001	.008	3	2
UCEC	PINCR →	+0.160	+1.900	<.001	<.001	3	2
SKCM	MZT1P1 →	+0.142	+3.449	<.001	.009	3	2
LUSC	RNU6-659P →	+0.316	+5.578	<.001	.002	3	2
LUSC	ELOCP22 →	+0.161	+4.503	.001	.005	3	2
BLCA	TRAJ29 →	+0.795	+5.788	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 959 associations by consensus.

PPIAP81 by ZNF362 expression — UCEC

Explore this box plot interactively →