Across TCGA patient cohorts, ZNF358 protein abundance is significantly associated with the RNA expression of many other genes, with 6,908 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ZNF358-associated genes across cancer lineages are ZNF555, ZNF433, and ZNF426. Each is linked with ZNF358 in more than 4 cancer types. Because this analysis shows association rather than direction, both ZNF358-to-partner and partner-to-ZNF358 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF358→partner) and Y-score (partner→ZNF358) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	ZNF555 →	+0.570	+0.326	<.001	<.001	3	5
CCRCC	ZNF433 →	+0.925	+0.535	.001	.003	3	5
BRCA	ZNF426 →	+0.625	+0.453	<.001	<.001	3	4
BRCA	ZNF791 →	+0.445	+0.398	<.001	.004	3	4
GBM	ZNF266 →	+0.636	+0.386	<.001	<.001	3	4
BRCA	ZNF493 →	+0.876	+0.378	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,908 associations by consensus.

Exploration

ZNF358 survival (RNA) · tumor vs normal (RNA) · all ZNF358 data types