ZNF354C

Across TCGA patient cohorts, ZNF354C protein abundance is significantly associated with the RNA expression of many other genes, with 720 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ZNF354C-associated genes across cancer lineages are ZNF585A, EP300, and ZBED4. Each is linked with ZNF354C in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF354C-to-partner and partner-to-ZNF354C results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF354C versus ZNF585A in GBM, with a Pearson correlation of 0.63.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF354C→partner) and Y-score (partner→ZNF354C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	ZNF585A →	+0.976	+0.431	.003	.004	3	2
GBM	EP300 →	+0.697	+0.324	.004	.006	3	1
GBM	ZBED4 →	+0.842	+0.455	<.001	<.001	3	1
GBM	KIAA0586 →	+0.540	+0.413	.004	<.001	3	1
GBM	SLC10A1 →	+1.077	+0.496	.001	<.001	3	1
GBM	ESRP2 →	+0.527	+0.435	.003	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 720 associations by consensus.

ZNF354C vs ZNF585A — GBM

Explore this scatter interactively →