ZNF354C

Across TCGA cell cohorts, ZNF354C mutation is significantly associated with the RNA expression of many other genes, with 160 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF354C-associated genes across cancer lineages are OR7G2, KCNA10, and CETN1. Each is linked with ZNF354C in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF354C-to-partner and partner-to-ZNF354C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR7G2 grouped by ZNF354C-low versus ZNF354C-high in STOMACH.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF354C→partner) and Y-score (partner→ZNF354C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	OR7G2 →	+0.100	+5.285	<.001	.003	3	2
BLOOD_Myeloma	KCNA10 →	+0.013	+4.807	<.001	.006	3	1
BLOOD_Myeloma	CETN1 →	+0.006	+4.807	<.001	.006	3	1
BLOOD_Myeloma	OPALIN →	+0.013	+4.807	<.001	.006	3	1
LARGE_INTESTINE	GCAT →	+1.247	+3.321	.001	.003	3	1
LARGE_INTESTINE	CA2 →	+1.999	+3.502	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 160 associations by consensus.

OR7G2 by ZNF354C expression — STOMACH

Explore this box plot interactively →