ZNF350-AS1

Across TCGA pan-cancer cohorts, ZNF350-AS1 RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated ZNF350-AS1 data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher ZNF350-AS1 RNA is associated with better overall survival. In most high-consensus cancer types, elevated ZNF350-AS1 expression acts as an unfavorable survival marker, although some lineages such as UVM and HNSC show a favorable association.

UVM, HNSC, and READ are the cancer types where ZNF350-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	OS	Tertile	II,III,IV	0.965	0.399	<.001	81	view →
HNSC	OS	Quartile	All	0.816	0.709	.012	44	view →
READ	OS	Median	II,III,IV	0.978	0.849	.005	39	view →
THYM	DFS	Median	II,III,IV	0.952	0.741	.001	37	view →
BLCA	OS	Quartile	All	0.691	0.539	.016	31	view →
ACC	DFS	Quartile	All	0.415	0.760	.004	25	view →
COAD	OS	Tertile	II,III,IV	0.934	0.778	.004	19	view →
UCS	DFS	Quartile	III,IV	0.539	0.079	.003	18	view →
GBM	DFS	Median	All	0.383	0.190	.007	17	view →
THCA	DFS	Tertile	All	0.971	0.897	.004	17	view →
DLBC	OS	Tertile	All	0.813	1.000	.023	12	view →
ESCA	OS	Median	All	0.584	0.761	.012	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

ZNF350-AS1–UVM (OS)

Open the UVM breakdown →