ZNF350-AS1

Across TCGA pan-cancer cohorts, ZNF350-AS1 RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of ZNF350-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where ZNF350-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types ZNF350-AS1 is over-expressed in tumor, although a few such as KIRP and KICH show the opposite, repressed pattern.

KIRP, KICH, and KIRC are the cancer types where ZNF350-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ZNF350-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRP	Male	II,III,IV	−1.980	<.001	11	view →
KICH	Male	II,III,IV	−1.887	<.001	10	view →
KIRC	Female	IV	−1.358	<.001	10	view →
LIHC	Female	III,IV	+0.248	<.001	8	view →
THCA	Male	III,IV	−1.364	.002	5	view →
BRCA	All	II,III,IV	+0.633	<.001	4	view →
PRAD	All	All	+0.845	.016	2	view →
PAAD	Female	All	−0.680	.036	2	view →
LUSC	Female	II,III,IV	−0.447	.001	2	view →
BLCA	Female	IV	+3.823	.002	1	view →
CHOL	All	All	+0.316	.027	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

ZNF350-AS1–KIRP

Open the KIRP breakdown →