ZNF35

Across TCGA cell cohorts, ZNF35 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,016 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ZNF35-associated GO terms across cancer lineages are DNA-templated transcription elongation, Mitotic spindle assembly, and Meiotic sister chromatid cohesion. Each is linked with ZNF35 in more than 13 cancer types. Because this analysis shows association rather than direction, both ZNF35-to-partner and partner-to-ZNF35 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA-templated transcription elongation grouped by ZNF35-low versus ZNF35-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF35→partner) and Y-score (partner→ZNF35) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	DNA-templated transcription elongation →	+0.088	+1.112	<.001	<.001	3	14
KIDNEY	Mitotic spindle assembly →	+0.092	+0.828	<.001	<.001	3	13
SOFT_TISSUE	Meiotic sister chromatid cohesion →	+0.157	+0.838	<.001	<.001	3	12
SOFT_TISSUE	Regulation of mRNA stability →	+0.061	+0.623	<.001	<.001	3	12
SOFT_TISSUE	Mitotic sister chromatid segregation →	+0.131	+0.762	<.001	<.001	3	11
SOFT_TISSUE	Sister chromatid cohesion →	+0.097	+0.661	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,016 associations by consensus.

DNA-templated transcription elongation by ZNF35 expression — OVARY

Explore this box plot interactively →