ZNF35

Across TCGA cell cohorts, ZNF35 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF35-associated genes across cancer lineages are PYDC2 and CD300H. Each is linked with ZNF35 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF35-to-partner and partner-to-ZNF35 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PYDC2 grouped by ZNF35-low versus ZNF35-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF35→partner) and Y-score (partner→ZNF35) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	PYDC2 →	+0.110	+5.247	<.001	.001	3	1
LARGE_INTESTINE	CD300H →	+0.039	+4.415	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

PYDC2 by ZNF35 expression — BLOOD_Lymphoma

Explore this box plot interactively →