Across TCGA patient cohorts, ZNF335 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,282 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ZNF335-associated proteins across cancer lineages are RBM12, PRCC, and RPRD1B. Each is linked with ZNF335 in more than 5 cancer types. Because this analysis shows association rather than direction, both ZNF335-to-partner and partner-to-ZNF335 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF335→partner) and Y-score (partner→ZNF335) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	RBM12 →	+0.241	+0.414	<.001	<.001	3	6
UCEC	PRCC →	+0.221	+0.723	.003	.001	3	5
LSCC	RPRD1B →	+0.304	+0.350	<.001	<.001	3	5
GBM	SF3B3 →	+0.264	+0.349	<.001	<.001	3	5
LSCC	ADNP →	+0.430	+0.508	<.001	<.001	3	5
LSCC	DDX27 →	+0.427	+0.388	<.001	.002	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,282 associations by consensus.

Exploration

ZNF335 survival (RNA) · tumor vs normal (RNA) · all ZNF335 data types