Across TCGA patient cohorts, ZNF335 protein abundance is significantly associated with the RNA expression of many other genes, with 856 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ZNF335-associated genes across cancer lineages are FAM83D, MITF, and TSPAN11. Each is linked with ZNF335 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF335-to-partner and partner-to-ZNF335 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF335→partner) and Y-score (partner→ZNF335) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	FAM83D →	+1.506	+1.118	.001	.003	3	2
GBM	MITF →	-1.356	-1.019	.008	.007	3	2
BRCA	TSPAN11 →	+0.745	+0.478	.001	<.001	3	1
BRCA	COMMD2 →	+0.441	+0.333	.001	.001	3	1
BRCA	GRB14 →	+2.174	+0.426	.007	.002	3	1
BRCA	CCDC88A →	+0.806	+0.431	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 856 associations by consensus.

Exploration

ZNF335 survival (RNA) · tumor vs normal (RNA) · all ZNF335 data types