Across TCGA cell cohorts, ZNF335 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,865 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZNF335-associated GO terms across cancer lineages are Chromosome separation, Promoter clearance during DNA-templated transcription, and RNA polymerase II promoter clearance. Each is linked with ZNF335 in more than 17 cancer types. Because this analysis shows association rather than direction, both ZNF335-to-partner and partner-to-ZNF335 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF335→partner) and Y-score (partner→ZNF335) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Chromosome separation →	+0.229	+0.975	<.001	<.001	3	18
SOFT_TISSUE	Promoter clearance during DNA-templated transcription →	+0.110	+0.664	<.001	.006	3	16
SOFT_TISSUE	RNA polymerase II promoter clearance →	+0.110	+0.664	<.001	.006	3	16
UPPER_AERODIGESTIVE_TRACT	Nucleic acid catabolic process →	+0.058	+0.990	<.001	<.001	3	16
BONE	Regulation of mRNA splicing, via spliceosome →	+0.080	+0.688	.001	<.001	3	16
LARGE_INTESTINE	Nuclear export →	+0.094	+0.816	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,865 associations by consensus.

Exploration

ZNF335 survival (RNA) · tumor vs normal (RNA) · all ZNF335 data types