Across TCGA cell cohorts, ZNF335 mutation is significantly associated with the RNA expression of many other genes, with 184 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF335-associated genes across cancer lineages are TRPV5, SLC25A28, and H1-8. Each is linked with ZNF335 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF335-to-partner and partner-to-ZNF335 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF335→partner) and Y-score (partner→ZNF335) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	TRPV5 →	+0.089	+3.874	.001	.003	3	2
LARGE_INTESTINE	SLC25A28 →	+0.474	+3.237	.001	.003	3	2
CNS	H1-8 →	+0.012	+4.035	<.001	.006	3	2
PANCREAS	LCE2A →	+0.025	+4.614	<.001	.004	3	1
PANCREAS	OR2J1 →	+0.005	+4.614	<.001	.004	3	1
PANCREAS	NAT8B →	+0.145	+4.011	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 184 associations by consensus.

Exploration

ZNF335 survival (RNA) · tumor vs normal (RNA) · all ZNF335 data types