ZNF333

Across TCGA patient cohorts, ZNF333 mutation is significantly associated with the RNA expression of many other genes, with 2,381 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF333-associated genes across cancer lineages are MIR4663, MIR4710, and RNU6-784P. Each is linked with ZNF333 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF333-to-partner and partner-to-ZNF333 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR4663 grouped by ZNF333-low versus ZNF333-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF333→partner) and Y-score (partner→ZNF333) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	MIR4663 →	+0.442	+4.346	.005	.007	3	3
BLCA	MIR4710 →	+0.446	+5.497	<.001	.004	3	3
LUSC	RNU6-784P →	+0.275	+3.485	<.001	.008	3	3
COAD	OR9Q2 →	+0.037	+4.399	<.001	.006	3	2
UCEC	NFU1 →	+0.409	+2.425	<.001	.001	3	2
UCEC	ZNF540 →	+0.237	+2.970	.002	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,381 associations by consensus.

MIR4663 by ZNF333 expression — HNSC

Explore this box plot interactively →