ZNF333

Across TCGA patient cohorts, ZNF333 mutation is significantly associated with the total protein of many other genes, with 31 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF333-associated genes across cancer lineages are Notch1, 14-3-3_beta, and eEF2. Each is linked with ZNF333 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF333-to-partner and partner-to-ZNF333 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Notch1 grouped by ZNF333-low versus ZNF333-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF333→partner) and Y-score (partner→ZNF333) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Notch1 →	+0.169	+1.920	<.001	.008	3	3
UCEC	14-3-3_beta →	-0.102	-3.558	.004	.002	3	1
UCEC	eEF2 →	+0.327	+2.115	.009	.017	3	1
UCEC	EGFR_pY1068 →	-0.277	-2.000	.001	.003	3	1
UCEC	A-Raf_pS299 →	-0.165	-3.700	<.001	.001	3	1
UCEC	Gab2 →	+0.260	+1.362	.039	.037	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 31 associations by consensus.

Notch1 by ZNF333 expression — UCEC

Explore this box plot interactively →