ZNF330

Across TCGA patient cohorts, ZNF330 mutation is significantly associated with the RNA expression of many other genes, with 2,106 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF330-associated genes across cancer lineages are CABS1, OR10P1, and OR11A1. Each is linked with ZNF330 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF330-to-partner and partner-to-ZNF330 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CABS1 grouped by ZNF330-low versus ZNF330-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF330→partner) and Y-score (partner→ZNF330) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	CABS1 →	+0.054	+5.010	<.001	.009	3	2
COAD	OR10P1 →	+0.259	+5.516	.002	.004	3	2
BLCA	OR11A1 →	+0.031	+3.680	<.001	.009	3	2
BLCA	DEFB135 →	+0.121	+4.859	<.001	.004	3	2
CESC	RNU1-6P →	+0.388	+5.969	<.001	.002	3	2
UCEC	RNA5SP412 →	+0.710	+2.774	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,106 associations by consensus.

CABS1 by ZNF330 expression — CESC

Explore this box plot interactively →