ZNF324B

Across TCGA patient cohorts, ZNF324B mutation is significantly associated with the total protein of many other genes, with 23 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF324B-associated genes across cancer lineages are mTOR_pS2448, TIGAR, and VHL. Each is linked with ZNF324B in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF324B-to-partner and partner-to-ZNF324B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, mTOR_pS2448 grouped by ZNF324B-low versus ZNF324B-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF324B→partner) and Y-score (partner→ZNF324B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	mTOR_pS2448 →	-0.123	-2.886	.017	.001	3	2
UCEC	TIGAR →	+0.132	+1.196	.012	.043	3	2
UCEC	VHL →	-0.509	-1.807	.030	.025	3	2
UCEC	ATM →	-0.522	-2.070	<.001	.001	3	2
UCEC	Caspase-8 →	-0.206	-2.880	.018	.001	3	2
UCEC	4E-BP1 →	+0.190	+2.029	.043	.017	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 23 associations by consensus.

mTOR_pS2448 by ZNF324B expression — UCEC

Explore this box plot interactively →