ZNF324B

Across TCGA cell cohorts, ZNF324B mutation is significantly associated with the RNA expression of many other genes, with 38 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF324B-associated genes across cancer lineages are TFDP3, DYNAP, and DIRAS2. Each is linked with ZNF324B in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF324B-to-partner and partner-to-ZNF324B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TFDP3 grouped by ZNF324B-low versus ZNF324B-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF324B→partner) and Y-score (partner→ZNF324B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	TFDP3 →	+0.013	+2.518	.009	.006	3	2
STOMACH	DYNAP →	+0.100	+4.129	<.001	.007	3	1
BLOOD_Leukemia	DIRAS2 →	+0.122	+4.087	<.001	.009	3	1
BLOOD_Leukemia	TACR3 →	+0.028	+4.060	<.001	.003	3	1
BLOOD_Leukemia	SOX1 →	+0.496	+4.564	<.001	.001	3	1
BLOOD_Leukemia	DEFB108B →	+0.129	+4.269	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 38 associations by consensus.

TFDP3 by ZNF324B expression — LARGE_INTESTINE

Explore this box plot interactively →